Creating EPUB files:
URLS: 
    http://www.ibm.com/developerworks/xml/tutorials/x-epubtut/section3.html
    http://www.manuel-strehl.de/dev/simple_epub_ebooks_with_python
    http://pypi.python.org/pypi/epubC/0.1.1
    http://www.epubbooks.com/blog/183/creating-an-epub-document
    http://threepress.org/document/epub-validate/

Structure

mimetype
META-INF/
   container.xml
OEBPS/
  content.opf
  title.html
  content.html
  stylesheet.css
  toc.ncx
  images/
     cover.png

mimetype:
application/epub+zip

META-INF/container.xml: 

<?xml version="1.0"?>
<container version="1.0" xmlns="urn:oasis:names:tc:opendocument:xmlns:container">
  <rootfiles>
    <rootfile full-path="OEBPS/content.opf"
     media-type="application/oebps-package+xml" />
  </rootfiles>
</container>

content.opf:

<?xml version='1.0' encoding='utf-8'?>
<package xmlns="http://www.idpf.org/2007/opf"
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            unique-identifier="bookid" version="2.0">
  <metadata>
    <dc:title>Hello World: My First EPUB</dc:title>
    <dc:creator>My Name</dc:creator>
    <dc:identifier
id="bookid">urn:uuid:0cc33cbd-94e2-49c1-909a-72ae16bc2658</dc:identifier>
    <dc:language>en-US</dc:language>
    <meta name="cover" content="cover-image" />
  </metadata>
  <manifest>
    <item id="ncx" href="toc.ncx" media-type="application/x-dtbncx+xml"/>
    <item id="cover" href="title.html" media-type="application/xhtml+xml"/>
    <item id="content" href="content.html"
media-type="application/xhtml+xml"/>
    <item id="cover-image" href="images/cover.png" media-type="image/png"/>
    <item id="css" href="stylesheet.css" media-type="text/css"/>
  </manifest>
  <spine toc="ncx">
    <itemref idref="cover" linear="no"/>
    <itemref idref="content"/>
  </spine>
  <guide>
    <reference href="title.html" type="cover" title="Cover"/>
  </guide>
</package>